RJ Hamster
Early Coverage: See Why (MTVA) Just Jumped On to…
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New on Our Radar: Market Crux Just Put (MTVA) This Morning’s Watchlist
See Why We Have All Eyes On (MTVA) Heading Into
Friday’s Session—February 13, 2026
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Pull Up (MTVA) While It’s Still Early…
February 13, 2026
Early Coverage | See Why (MTVA) Just Jumped On to Our Morning Watchlist
Dear Reader,
Healthcare is entering a period where metabolic dysfunction—and the downstream conditions it drives—has moved to the center of chronic disease strategy.
That shift is showing up not just in clinical priorities, but in the size and momentum of multiple therapeutic categories tied to weight, glucose regulation, and liver health.
Start with obesity: the anti-obesity therapeutics market is projected to expand at a 29.2% CAGR, reaching $67.16B by 2034. The broader cardiometabolic landscape is also moving higher, with the global cardiometabolic therapeutics market expected to grow from $68.4B in 2026 to over $111B by 2035.
Diabetes remains a major pillar within that ecosystem. The global T2D therapeutics market is forecast to reach $76.39B by 2034, while the broader diabetes therapeutics category is projected as high as $283.36B over the same timeframe.
Liver disease adds another fast-growing layer. The MASH (Metabolic Dysfunction-Associated Steatohepatitis) therapeutics market—often described as a condition that can progress quietly for years—is projected to rise from $12.7B in 2026 to $92.5B by 2034.
Similar categories, including broader liver disease therapeutics (projected $50.4B by 2034) and inflammatory disease therapeutics (projected $293.4B by 2035), reinforce how interconnected these pathways have become.
And increasingly, that interconnected biology is being mapped with computational tools. AI-modeling collaborations are now being used to identify and validate disease targets across inflammation and cardiometabolic pathways—sometimes surfacing signals that overlap with fields like oncology, a market projected at $667.28B.
Against this backdrop, MetaVia Inc. (Nasdaq: MTVA) is advancing clinical-stage programs aimed at obesity and liver disease, and has reported results from an AI-modeling collaboration that aligns its work with key inflammatory and cardiometabolic targets.
That’s part of why (MTVA) is topping our watchlist this morning—Friday, February 13, 2026.
But keep in mind, (MTVA) has less than 985K shares listed as available to the public. When companies have a razor-thin float like this, the potential exists for sharp moves if demand begins to shift.
Right now, (MTVA) is sitting below $2and appears to be flying under the radar of many screens.
That’s where it can help to look at what the chart is signaling in the near term—especially when sentiment has cooled.
Technical readings show the RSI levels for (MTVA) have drifted below 30 for its 9-day, 14-day, and 20-day time-frames—levels that some would describe as near “oversold territory”, which could indicate a potential trend reversal is in the works.
And when a company posts attention-grabbing clinical news in massive therapeutic categories, it’s not unusual for analyst commentary to turn sharply more ambitious—sometimes very quickly.
Recent Analyst Targets Suggest 3,000% to 3,400% Upside Potential
Several biotechnology analysts have begun to set targets that suggest (MTVA) is significantly overlooked relative to its recent clinical success:
- Maxim Group: Analyst Jason McCarthy, Ph.D., has set a $55 target on MTVA, suggesting over 3,000% upside potential from its recent range.
- Zacks SCR: Analyst David Bautz, Ph.D., has set a $60 target on MTVA, suggesting over 3,400% upside potential.
Taken together—large, fast-expanding therapeutic categories, recent clinical updates, and AI-enabled validation—(MTVA) is starting to look like one of those under-followed stories that can change quickly once more people connect the dots.
Before we go any further, it helps to understand exactly what (MTVA) is building and why its approach is different.
Company Overview: Engineering the Future of Metabolic Health
MetaVia Inc. (Nasdaq: MTVA) is a clinical-stage biotechnology companydedicated to transforming the treatment of cardiometabolic diseases. Formerly known as NeuroBo Pharmaceuticals, the company underwent a strategic rebranding to MetaVia to better align with its focus on the “Metabolic-Vascular” axis.
Headquartered in Cambridge, MA, the company operates with a high-efficiency team and deep strategic ties to South Korean pharmaceutical giant Dong-A ST.
What makes (MTVA) distinctive is its reliance on “dual-agonist” and “gut-pep-tide” engineering. Its lead candidate, DA-1726, is a novel oxyntomodulin (OXM) analogue that simultaneously activates the glucagon-like pep-tide-1 receptor (GLP1R) and the glucagon receptor (GCGR).
While first-generation treatments often prioritize appetite suppression alone, DA-1726 aims to decrease food intake while increasing energy expenditure. This dual action mimics the body’s natural gut hormones to potentially produce superior weight loss and metabolic improvement compared to selective GLP1R agonists.
Simultaneously, the company is advancing vanoglipel (DA-1241), a novel G-protein-coupled receptor 119 (GPR119) agonist. This oral therapy promotes the release of endogenous GLP-1, GIP, and PYY. In clinical studies, vanoglipel has demonstrated the ability to reduce liver inflammation and fibrosis, providing a powerful one-two punch against MASH and Type 2 diabetes.
Best-in-Class Potential: The DA-1726 Breakthrough
In January 2026, (MTVA) releasedstatistically significant results from its Phase 1b trial of DA-1726. The data from an 8-week cohort was nothing short of remarkable: patients achieved a 9.1%reduction in body weight (averaging 21.2 lbs) and a nearly 10 cm (3.8 inch) reduction in waist circumference.
Furthermore, the trial showed a 23.7%reduction in liver stiffness (VCTE) in just 54 days. These results highlight the “glucagon effect”—where increasing energy expenditure targets visceral fatand liver health more aggressively than standard therapies.
With no treatment-related discontinuations and a favorable safety profile, MTVA is setting a high bar for the next generation of weight-loss solutions.
AI-Driven Precision: The Syntekabio Collaboration
The company’s recent February 4, 2026 announcement confirmed that its collaboration with Syntekabio is yielding high-value insights. Using the DeepMatcher® AI platform, (MTVA)confirmed that vanoglipel strongly engages inflammatory and cardiometabolic target pathways.
This validation is critical for the upcomingPhase 2b studies and potentially opens the door to oncology applications, as the AI identified strong anti-inflammatory signatures that could address cancer-related pathways.
Financial Strength and Execution Runway
(MTVA) began 2026 by completing a $9.3M underwritten public offering, including the full exercise of the over-allotment option, adding capital intended for working capital and the continued clinical development of DA-1726.
Readers who want the full structure and terms can review the company’s announcement here.
The management team, led by CEOHyung Heon Kim and Chairman Andrew Koven—a former executive at Warner-Lambert and Merck—possesses the clinical and operational depth required to transition from a mid-stage biotech to a commercial-stage contender.
7 Reasons Why (MTVA) is Topping Our Watchlist This Morning
—Friday, February 13, 2026.
1. Analyst Attention: Following recent clinical updates, (MTVA) has drawn published targets from multiple biotechnology analysts that imply roughly 3,000% to 3,400% upside potential versus the range referenced in your text.
2. Limited Float: (MTVA) has fewer than 985K shares listed as available to the public, a structure that can heighten sensitivity to changing attention.
3. Technical Setup: (MTVA) recently showed RSI readings below 30 across multiple timeframes, levels some associate with “oversold territory” and a setup for a potential trend reversal.
4. Massive End-Markets: Across obesity ($67.16B by 2034), cardiometabolic therapeutics (over $111B by 2035), T2D therapeutics ($76.39B by 2034), and MASH therapeutics ($92.5B by 2034), (MTVA) is positioning itself within multiple large categories projected to expand over the next decade.
5. Clinical Momentum: (MTVA)reported statistically significant Phase 1b results showing measurable reductions in body weight, waist circumference, and liver stiffness within 8 weeks.
6. Dual Programs: (MTVA) is advancing two distinct clinical-stage candidates—DA-1726 and vanoglipel—addressing both metabolic and liver-related conditions.
7. AI Validation: (MTVA) has confirmed through an AI-modeling collaboration that its biology aligns with key inflammatory and cardiometabolic targets.
Pull Up (MTVA) While It’s Still Early…
In the world of high-stakes biotechnology, data is the only currency that matters. MetaVia Inc. (Nasdaq: MTVA) has consistently delivered clinical results that not only meet but often exceed expectations for mid-stage candidates.
The company’s ability to target the most lucrative sectors in healthcare—obesity and liver disease—while leveraging AI-driven precision sets it apart from a sea of competitors.
As MTVA advances toward its titration studies in late 2026 and further Phase 2b MASH milestones, the narrative of a transformation in cardiometabolic health is becoming impossible to ignore.
For anyone closely monitoring the future of weight loss and metabolic restoration, (MTVA) is a symbol that could demand immediate attention as its clinical story continues to unfold.
We have all eyes on (MTVA) this morning—Friday, February 13, 2026.
Consider starting your own research on (MTVA) while it’s still early.
Also, keep a lookout for my next update, it could be coming very shortly.
Sincerely,
Gary Silver
Managing Editor,
Market Crux
MarketCrux.com (“MarketCrux” or “MC” ) is owned by Headline Media LLC, MC is not responsible for its accuracy. Make sure to always do your own research and due diligence on any day and swing profile MC brings to your attention. Any emojis used do not have a specific defined meaning, and may be used inconsistently. We do not provide personalized in-vest-ment advice, are not in-vest-ment advisors, and any profiles we mention are not suitable for all in-vest-ors.
Pursuant to an agreement between Headline Media LLC and TD Media LLC, Headline Media LLC has been hired for a period beginning on 02/13/2026 and ending on 02/13/2026 to publicly disseminate information about (MTVA:US) via digital communications. Under this agreement, TD Media LLC has paid Headline Media LLC seven thousand five hundred USD (“Funds”). These Funds were part of the thirty five thousand USD funds that TD Media LLC received from a third party named JRZ Capital LLC who did receive the Funds directly or indirectly from the Issuer and does not own stock in the Issuer but the reader should assume that the clients of the third party own shares in the Issuer, which they will liquidate at or near the time you receive this communication and has the potential to hurt share prices.
Neither Headline Media LLC, TD Media LLC and their member own shares of (MTVA:US).
Please see important disclosure information here: https://marketcrux.com/disclosure/mtva-DEPiO/#detailsHeadline Media7901 4th Street NSuite 300St. Petersburg, FL 33702UnsubscribeUpdate Profile | Constant Contact Data NoticeSent by gary@marketcrux.net
Any content you receive is for information purposes only. Always conduct your own research.
*Sponsored
New on Our Radar: Market Crux Just Put (MTVA) This Morning’s Watchlist
See Why We Have All Eyes On (MTVA) Heading Into
Friday’s Session—February 13, 2026
Don’t Miss The Next Breakout—Get Real-Time Alerts Sent Directly
To Your Phone. Up To 10X Faster Than Email.
Pull Up (MTVA) While It’s Still Early…
February 13, 2026
Early Coverage | See Why (MTVA) Just Jumped On to Our Morning Watchlist
Dear Reader,
Healthcare is entering a period where metabolic dysfunction—and the downstream conditions it drives—has moved to the center of chronic disease strategy.
That shift is showing up not just in clinical priorities, but in the size and momentum of multiple therapeutic categories tied to weight, glucose regulation, and liver health.
Start with obesity: the anti-obesity therapeutics market is projected to expand at a 29.2% CAGR, reaching $67.16B by 2034. The broader cardiometabolic landscape is also moving higher, with the global cardiometabolic therapeutics market expected to grow from $68.4B in 2026 to over $111B by 2035.
Diabetes remains a major pillar within that ecosystem. The global T2D therapeutics market is forecast to reach $76.39B by 2034, while the broader diabetes therapeutics category is projected as high as $283.36B over the same timeframe.
Liver disease adds another fast-growing layer. The MASH (Metabolic Dysfunction-Associated Steatohepatitis) therapeutics market—often described as a condition that can progress quietly for years—is projected to rise from $12.7B in 2026 to $92.5B by 2034.
Similar categories, including broader liver disease therapeutics (projected $50.4B by 2034) and inflammatory disease therapeutics (projected $293.4B by 2035), reinforce how interconnected these pathways have become.
And increasingly, that interconnected biology is being mapped with computational tools. AI-modeling collaborations are now being used to identify and validate disease targets across inflammation and cardiometabolic pathways—sometimes surfacing signals that overlap with fields like oncology, a market projected at $667.28B.
Against this backdrop, MetaVia Inc. (Nasdaq: MTVA) is advancing clinical-stage programs aimed at obesity and liver disease, and has reported results from an AI-modeling collaboration that aligns its work with key inflammatory and cardiometabolic targets.
That’s part of why (MTVA) is topping our watchlist this morning—Friday, February 13, 2026.
But keep in mind, (MTVA) has less than 985K shares listed as available to the public. When companies have a razor-thin float like this, the potential exists for sharp moves if demand begins to shift.
Right now, (MTVA) is sitting below $2and appears to be flying under the radar of many screens.
That’s where it can help to look at what the chart is signaling in the near term—especially when sentiment has cooled.
Technical readings show the RSI levels for (MTVA) have drifted below 30 for its 9-day, 14-day, and 20-day time-frames—levels that some would describe as near “oversold territory”, which could indicate a potential trend reversal is in the works.
And when a company posts attention-grabbing clinical news in massive therapeutic categories, it’s not unusual for analyst commentary to turn sharply more ambitious—sometimes very quickly.
Recent Analyst Targets Suggest 3,000% to 3,400% Upside Potential
Several biotechnology analysts have begun to set targets that suggest (MTVA) is significantly overlooked relative to its recent clinical success:
- Maxim Group: Analyst Jason McCarthy, Ph.D., has set a $55 target on MTVA, suggesting over 3,000% upside potential from its recent range.
- Zacks SCR: Analyst David Bautz, Ph.D., has set a $60 target on MTVA, suggesting over 3,400% upside potential.
Taken together—large, fast-expanding therapeutic categories, recent clinical updates, and AI-enabled validation—(MTVA) is starting to look like one of those under-followed stories that can change quickly once more people connect the dots.
Before we go any further, it helps to understand exactly what (MTVA) is building and why its approach is different.
Company Overview: Engineering the Future of Metabolic Health
MetaVia Inc. (Nasdaq: MTVA) is a clinical-stage biotechnology companydedicated to transforming the treatment of cardiometabolic diseases. Formerly known as NeuroBo Pharmaceuticals, the company underwent a strategic rebranding to MetaVia to better align with its focus on the “Metabolic-Vascular” axis.
Headquartered in Cambridge, MA, the company operates with a high-efficiency team and deep strategic ties to South Korean pharmaceutical giant Dong-A ST.
What makes (MTVA) distinctive is its reliance on “dual-agonist” and “gut-pep-tide” engineering. Its lead candidate, DA-1726, is a novel oxyntomodulin (OXM) analogue that simultaneously activates the glucagon-like pep-tide-1 receptor (GLP1R) and the glucagon receptor (GCGR).
While first-generation treatments often prioritize appetite suppression alone, DA-1726 aims to decrease food intake while increasing energy expenditure. This dual action mimics the body’s natural gut hormones to potentially produce superior weight loss and metabolic improvement compared to selective GLP1R agonists.
Simultaneously, the company is advancing vanoglipel (DA-1241), a novel G-protein-coupled receptor 119 (GPR119) agonist. This oral therapy promotes the release of endogenous GLP-1, GIP, and PYY. In clinical studies, vanoglipel has demonstrated the ability to reduce liver inflammation and fibrosis, providing a powerful one-two punch against MASH and Type 2 diabetes.
Best-in-Class Potential: The DA-1726 Breakthrough
In January 2026, (MTVA) releasedstatistically significant results from its Phase 1b trial of DA-1726. The data from an 8-week cohort was nothing short of remarkable: patients achieved a 9.1%reduction in body weight (averaging 21.2 lbs) and a nearly 10 cm (3.8 inch) reduction in waist circumference.
Furthermore, the trial showed a 23.7%reduction in liver stiffness (VCTE) in just 54 days. These results highlight the “glucagon effect”—where increasing energy expenditure targets visceral fatand liver health more aggressively than standard therapies.
With no treatment-related discontinuations and a favorable safety profile, MTVA is setting a high bar for the next generation of weight-loss solutions.
AI-Driven Precision: The Syntekabio Collaboration
The company’s recent February 4, 2026 announcement confirmed that its collaboration with Syntekabio is yielding high-value insights. Using the DeepMatcher® AI platform, (MTVA)confirmed that vanoglipel strongly engages inflammatory and cardiometabolic target pathways.
This validation is critical for the upcomingPhase 2b studies and potentially opens the door to oncology applications, as the AI identified strong anti-inflammatory signatures that could address cancer-related pathways.
Financial Strength and Execution Runway
(MTVA) began 2026 by completing a $9.3M underwritten public offering, including the full exercise of the over-allotment option, adding capital intended for working capital and the continued clinical development of DA-1726.
Readers who want the full structure and terms can review the company’s announcement here.
The management team, led by CEOHyung Heon Kim and Chairman Andrew Koven—a former executive at Warner-Lambert and Merck—possesses the clinical and operational depth required to transition from a mid-stage biotech to a commercial-stage contender.
7 Reasons Why (MTVA) is Topping Our Watchlist This Morning
—Friday, February 13, 2026.
1. Analyst Attention: Following recent clinical updates, (MTVA) has drawn published targets from multiple biotechnology analysts that imply roughly 3,000% to 3,400% upside potential versus the range referenced in your text.
2. Limited Float: (MTVA) has fewer than 985K shares listed as available to the public, a structure that can heighten sensitivity to changing attention.
3. Technical Setup: (MTVA) recently showed RSI readings below 30 across multiple timeframes, levels some associate with “oversold territory” and a setup for a potential trend reversal.
4. Massive End-Markets: Across obesity ($67.16B by 2034), cardiometabolic therapeutics (over $111B by 2035), T2D therapeutics ($76.39B by 2034), and MASH therapeutics ($92.5B by 2034), (MTVA) is positioning itself within multiple large categories projected to expand over the next decade.
5. Clinical Momentum: (MTVA)reported statistically significant Phase 1b results showing measurable reductions in body weight, waist circumference, and liver stiffness within 8 weeks.
6. Dual Programs: (MTVA) is advancing two distinct clinical-stage candidates—DA-1726 and vanoglipel—addressing both metabolic and liver-related conditions.
7. AI Validation: (MTVA) has confirmed through an AI-modeling collaboration that its biology aligns with key inflammatory and cardiometabolic targets.
Pull Up (MTVA) While It’s Still Early…
In the world of high-stakes biotechnology, data is the only currency that matters. MetaVia Inc. (Nasdaq: MTVA) has consistently delivered clinical results that not only meet but often exceed expectations for mid-stage candidates.
The company’s ability to target the most lucrative sectors in healthcare—obesity and liver disease—while leveraging AI-driven precision sets it apart from a sea of competitors.
As MTVA advances toward its titration studies in late 2026 and further Phase 2b MASH milestones, the narrative of a transformation in cardiometabolic health is becoming impossible to ignore.
For anyone closely monitoring the future of weight loss and metabolic restoration, (MTVA) is a symbol that could demand immediate attention as its clinical story continues to unfold.
We have all eyes on (MTVA) this morning—Friday, February 13, 2026.
Consider starting your own research on (MTVA) while it’s still early.
Also, keep a lookout for my next update, it could be coming very shortly.
Sincerely,
Gary Silver
Managing Editor,
Market Crux
MarketCrux.com (“MarketCrux” or “MC” ) is owned by Headline Media LLC, MC is not responsible for its accuracy. Make sure to always do your own research and due diligence on any day and swing profile MC brings to your attention. Any emojis used do not have a specific defined meaning, and may be used inconsistently. We do not provide personalized in-vest-ment advice, are not in-vest-ment advisors, and any profiles we mention are not suitable for all in-vest-ors.
Pursuant to an agreement between Headline Media LLC and TD Media LLC, Headline Media LLC has been hired for a period beginning on 02/13/2026 and ending on 02/13/2026 to publicly disseminate information about (MTVA:US) via digital communications. Under this agreement, TD Media LLC has paid Headline Media LLC seven thousand five hundred USD (“Funds”). These Funds were part of the thirty five thousand USD funds that TD Media LLC received from a third party named JRZ Capital LLC who did receive the Funds directly or indirectly from the Issuer and does not own stock in the Issuer but the reader should assume that the clients of the third party own shares in the Issuer, which they will liquidate at or near the time you receive this communication and has the potential to hurt share prices.
Neither Headline Media LLC, TD Media LLC and their member own shares of (MTVA:US).
Please see important disclosure information here: https://marketcrux.com/disclosure/mtva-DEPiO/#detailsHeadline Media7901 4th Street NSuite 300St. Petersburg, FL 33702UnsubscribeUpdate Profile | Constant Contact Data NoticeSent by gary@marketcrux.net
